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Healthy aging is a journey and a process. Read articles on treating bladder problems, slowing dementia and understanding health issues related to aging.
Updated: 10 min 48 sec ago

Aluminum is intricately associated with the neuropathology of familial Alzheimer's disease

Fri, 04/09/2021 - 22:17
A new study continues to support a growing body of evidence that aluminum contributes to the pathogenesis of Alzheimer's disease (AD). Researchers found aluminum co-located with phosphorylated tau protein, which is an early initiator of AD.

PLD3 gene contributes to risk of Alzheimer's disease

Fri, 04/09/2021 - 01:06
A rare and controversial mutation in the phospholipase D3 (PLD3) protein -- previously linked to Alzheimer's disease -- interferes with PLD3's vital recycling function inside neurons, according to a new study.

Leaking calcium in neurons an early sign of Alzheimer's pathology

Fri, 04/09/2021 - 00:53
Alzheimer's disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease's ravages, while others remain resilient?

One in ten have long-term effects 8 months following mild COVID-19

Thu, 04/08/2021 - 03:13
Eight months after mild COVID-19, one in ten people still has at least one moderate to severe symptom that is perceived as having a negative impact on their work, social or home life, according to a new study. The most common long-term symptoms are a loss of smell and taste and fatigue.

An amyloid link between Parkinson's disease and melanoma

Wed, 04/07/2021 - 18:06
On the surface, Parkinson's disease and melanoma do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease patients are more likely to develop melanoma than the general population. Now, scientists report a molecular link between the two diseases in the form of protein aggregates known as amyloids.

Accelerated cellular aging associated with early mortality seen in depressed individuals

Tue, 04/06/2021 - 23:29
Cells from individuals with Major Depressive Disorder (MDD) were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a new study.

Keep pace: Walking with a partner is great but might slow you down

Fri, 04/02/2021 - 23:47
A new study shows that couples often decreased their speed when walking together. Speed further decreased if they were holding hands.

Thirteen new Alzheimer's genes identified in human genome study

Fri, 04/02/2021 - 18:12
Prior known Alzheimer's genes have been associated with amyloid accumulation and neuroinflammation. A cutting-edge technique known as whole genome sequencing was used to identify new, rare gene variants associated with Alzheimer's disease. Findings could suggest new targets for drug development aimed at enhancing neuroplasticity and the stability of synapses.

How brain cells repair their DNA reveals 'hot spots' of aging and disease

Fri, 04/02/2021 - 00:42
Neurons lack the ability to replicate their DNA, so they're constantly working to repair damage to their genome. A new study finds that these repairs are not random, but instead focus on protecting certain genetic 'hot spots' that appear to play a critical role in neural identity and function.

Friends and enemies 'make sense' for long-lived animals

Tue, 03/30/2021 - 21:42
It makes evolutionary sense for long-lived animals to have complex social relationships - such as friends and enemies - researchers say.

Selenium supplementation protects against obesity and may extend lifespan

Tue, 03/30/2021 - 21:42
Adding the nutrient selenium to diets protects against obesity and provides metabolic benefits to mice, according to a new study.

Chronic viral infections can have lasting effects on human immunity, similar to aging

Tue, 03/30/2021 - 01:03
Research suggests that chronic viral infections have a profound and lasting impact on the immune system in ways that are similar to those seen during aging. Using systems immunology and artificial intelligence, researchers profiled and compared immune responses in a cohort of aging individuals, people with HIV on anti-retroviral therapy, and people infected with hepatitis C before and after the virus was treated with a drug that has up to a 97% cure rate.

GlyNAC improves multiple defects in aging to boost strength and cognition in older humans

Mon, 03/29/2021 - 21:57
GlyNAC - a combination precursors of the natural antioxidant glutathione - improved many age-associated defects in older humans boosting muscle strength and cognition.

Signals from muscle protect from dementia

Sat, 03/27/2021 - 00:53
Scientists are studying how signals sent from skeletal muscle affect the brain.

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

Fri, 03/26/2021 - 00:32
A researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.

Women accumulate Alzheimer's-related protein faster

Thu, 03/25/2021 - 21:24
Alzheimer's disease seems to progress faster in women than in men. The protein tau accumulates at a higher rate in women.

Common Alzheimer's treatment linked to slower cognitive decline

Thu, 03/25/2021 - 21:24
Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study shows persisting cognitive benefits and reduced mortality for up to five years after diagnosis.

Anabolic androgenic steroids accelerate brain aging

Thu, 03/25/2021 - 18:15
Anabolic androgenic steroids (AAS), a synthetic version of the male sex hormone testosterone, are sometimes used as a medical treatment for hormone imbalance, and its use is known to have many side effects, ranging from acne to heart problems to increased aggression. A new study now suggests that AAS can also have deleterious effects on the brain, causing it to age prematurely.

BMI1, a promising gene to protect against Alzheimer's disease

Wed, 03/24/2021 - 00:37
A molecular biologist discovers a new function for BMI1, which is known to counteract brain aging.

Exercise boosts blood flow to the brain, study finds

Tue, 03/23/2021 - 22:42
It's not just your legs and heart that get a workout when you walk briskly; exercise affects your brain as well. A new study shows that when older adults with mild memory loss followed an exercise program for a year, the blood flow to their brains increased.