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Read the latest research on Alzheimer's disease. Learn about Alzheimer's symptoms such as memory loss and senile dementia. Find out about Alzheimer's stages, causes and new treatments.
Updated: 14 min 29 sec ago

Aluminum is intricately associated with the neuropathology of familial Alzheimer's disease

Fri, 04/09/2021 - 22:17
A new study continues to support a growing body of evidence that aluminum contributes to the pathogenesis of Alzheimer's disease (AD). Researchers found aluminum co-located with phosphorylated tau protein, which is an early initiator of AD.

Fighting dementia with play

Fri, 04/09/2021 - 19:06
A dementia diagnosis turns the world upside down, not only for the person affected but also for their relatives, as brain function gradually declines. Those affected lose their ability to plan, remember things or behave appropriately. At the same time, their motor skills also deteriorate. Ultimately, dementia patients are no longer able to handle daily life alone and need comprehensive care. New research shows that cognitive motor training helps in the fight against Alzheimer's and dementia.

PLD3 gene contributes to risk of Alzheimer's disease

Fri, 04/09/2021 - 01:06
A rare and controversial mutation in the phospholipase D3 (PLD3) protein -- previously linked to Alzheimer's disease -- interferes with PLD3's vital recycling function inside neurons, according to a new study.

Leaking calcium in neurons an early sign of Alzheimer's pathology

Fri, 04/09/2021 - 00:53
Alzheimer's disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease's ravages, while others remain resilient?

Artificial Intelligence could 'crack the language of cancer and Alzheimer's'

Thu, 04/08/2021 - 22:44
Powerful algorithms can 'predict' the biological language of cancer and neurodegenerative diseases like Alzheimer's, scientists have found. Big data produced during decades of research was fed into a computer language model to see if artificial intelligence can make more advanced discoveries than humans.

An amyloid link between Parkinson's disease and melanoma

Wed, 04/07/2021 - 18:06
On the surface, Parkinson's disease and melanoma do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease patients are more likely to develop melanoma than the general population. Now, scientists report a molecular link between the two diseases in the form of protein aggregates known as amyloids.

Genetic link between face and brain shape

Mon, 04/05/2021 - 21:06
Researchers have identified 76 overlapping genetic locations that shape both our face and our brain. What the researchers didn't find is evidence that this genetic overlap also predicts someone's behavioral-cognitive traits or risk of conditions such as Alzheimer's disease. This means that the findings help to debunk several persistent pseudoscientific claims about what our face reveals about us.

Thirteen new Alzheimer's genes identified in human genome study

Fri, 04/02/2021 - 18:12
Prior known Alzheimer's genes have been associated with amyloid accumulation and neuroinflammation. A cutting-edge technique known as whole genome sequencing was used to identify new, rare gene variants associated with Alzheimer's disease. Findings could suggest new targets for drug development aimed at enhancing neuroplasticity and the stability of synapses.

How brain cells repair their DNA reveals 'hot spots' of aging and disease

Fri, 04/02/2021 - 00:42
Neurons lack the ability to replicate their DNA, so they're constantly working to repair damage to their genome. A new study finds that these repairs are not random, but instead focus on protecting certain genetic 'hot spots' that appear to play a critical role in neural identity and function.

Experimental antibodies for Parkinson's, Alzheimer's may cause harmful inflammation

Tue, 03/30/2021 - 01:03
Scientists find evidence that antibody-based treatments in clinical trials for neurodegenerative diseases may trigger an inflammatory response in human brain immune cells, eroding their positive effects.

GlyNAC improves multiple defects in aging to boost strength and cognition in older humans

Mon, 03/29/2021 - 21:57
GlyNAC - a combination precursors of the natural antioxidant glutathione - improved many age-associated defects in older humans boosting muscle strength and cognition.

Signals from muscle protect from dementia

Sat, 03/27/2021 - 00:53
Scientists are studying how signals sent from skeletal muscle affect the brain.

Controlled scar formation in the brain

Fri, 03/26/2021 - 20:16
When the brain suffers injury or infection, glial cells surrounding the affected site act to preserve the brain's sensitive nerve cells and prevent excessive damage. A team of researchers has been able to demonstrate the important role played by the reorganization of the structural and membrane elements of glial cells.

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

Fri, 03/26/2021 - 00:32
A researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.

Women accumulate Alzheimer's-related protein faster

Thu, 03/25/2021 - 21:24
Alzheimer's disease seems to progress faster in women than in men. The protein tau accumulates at a higher rate in women.

Common Alzheimer's treatment linked to slower cognitive decline

Thu, 03/25/2021 - 21:24
Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study shows persisting cognitive benefits and reduced mortality for up to five years after diagnosis.

Non-drug therapies as good as or better than drugs for treating depression in people with dementia

Thu, 03/25/2021 - 05:21
Non-drug therapies, such as exercise, appear to be as, or more, effective than drugs for reducing symptoms of depression in people with dementia, suggests new research.

BMI1, a promising gene to protect against Alzheimer's disease

Wed, 03/24/2021 - 00:37
A molecular biologist discovers a new function for BMI1, which is known to counteract brain aging.

'Zombie' genes? Research shows some genes come to life in the brain after death

Tue, 03/23/2021 - 22:42
Researchers analyzed gene expression in fresh brain tissue and found that gene expression in some cells actually increased after death.

Exercise boosts blood flow to the brain, study finds

Tue, 03/23/2021 - 22:42
It's not just your legs and heart that get a workout when you walk briskly; exercise affects your brain as well. A new study shows that when older adults with mild memory loss followed an exercise program for a year, the blood flow to their brains increased.