Read the latest research on Alzheimer's disease. Learn about Alzheimer's symptoms such as memory loss and senile dementia. Find out about Alzheimer's stages, causes and new treatments.
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Scientists have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands of people across the globe. The study also has implications for a much wider suite of neurological disorders associated with aging.
A proof-of-concept study conducted in a mouse model of Alzheimer's disease offers new evidence that copper isotopes can be used to detect the amyloid-beta protein deposits that form in the brains of people living with -- or at risk of developing -- Alzheimer's.
Researchers used a variety of advanced drug screening techniques to test out more than 10,000 compounds in search of a cure. To their surprise, they found that the widely used antibiotic methacycline was effective at preventing brain infections and reducing neurological problems associated with the virus in mice.
Anxiety is associated with an increased rate of progression from mild cognitive impairment to Alzheimer's disease, according to a new study.
A research team has discovered that Dlgap2, a gene that helps facilitate communication between neurons in the nervous system, is associated with the degree of memory loss in mice and risk for Alzheimer's dementia in humans. When studying post-mortem human brain tissue, the researchers also discovered low levels of Dlgap2 in people experiencing 'poorer cognitive health' and 'faster cognitive decline' prior to death.
Biochemists have proposed that degenerative diseases as varied as Alzheimer's, Parkinson's and muscle atrophy occur in two distinct phases marked by protein signaling changes that could result in patients responding differently to the same treatment.
A simple eye exam combined with powerful artificial intelligence (AI) machine learning technology could provide early detection of Parkinson's disease, according to new research.
While the broad architecture and organization of the human brain is universal, new research shows how the differences between how people reimagine common scenarios can be observed in brain activity and quantified. These unique neurological signatures could ultimately be used to understand, study, and even improve treatment of disorders such as Alzheimer's disease.
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy.
Older women who live in locations with higher levels of air pollution may have more brain shrinkage, the kind seen in Alzheimer's disease, than women who live in locations with lower levels, according to a new study.
Researchers find a key mutation causing abnormal transport of BACE1, the enzyme responsible for processing the Alzheimer's disease-linked amyloid protein. Identification of this mutation, which is more common among African Americans with Alzheimer's, may allow early intervention.
An experimental Alzheimer's disease treatment is proving effective at treating some of the most persistent, life-threatening antibiotic-resistant bacteria. Researchers have discovered that the drug called PBT2 is effective at disrupting and killing a class of bacteria - known as Gram-negative bacteria - that cause infections such as pneumonia, bloodstream infections and meningitis.
New research explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease (AD).
In a study of women aged 80 years and older, living in locations with higher exposures to air pollution was associated with increased depressive symptoms.
A study has identified certain regions in the retina - the lining found in the back of the eye - that are more affected by Alzheimer's disease than other areas. The findings may help physicians predict changes in the brain as well as cognitive deterioration, even for patients experiencing the earliest signs of mild impairment.
Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers now show that this chain reaction starts much earlier in mice than commonly assumed.
New research into how a common parasite infection alters human behavior could help development of treatments for schizophrenia and other neurological disorders. T. gondii currently infects 2.5 billion people worldwide and causes the disease Toxoplasmosis.
Researchers have demonstrated that the severity of 'reactive astrocytes' is a key indicator for the onset of Alzheimer's disease.
In recent years, the scientific community has suspected that the gut microbiota plays a role in the development of the disease. A team now confirms the correlation, in humans, between an imbalance in the gut microbiota and the development of amyloid plaques in the brain, which are at the origin of Alzheimer's disease.
Exercising more than once per week is associated with a lower risk of developing Alzheimer's disease in patients with mild cognitive impairment.